Stable polymorph of morphine1

نویسندگان

  • Thomas Gelbrich
  • Doris E. Braun
  • Ulrich J. Griesser
چکیده

In the stable polymorph of the title compound, C17H19NO3 [systematic name: (5α,6α)-7,8-didehydro-4,5-ep-oxy-17-methyl-morphinan-3,6-diol], the mol-ecular conformation is in agreement with the characteristics of previously reported morphine forms. The molecule displays the typical T-shape and its piperidine ring adopts a slightly distorted chair conformation. Inter-molecular O-H⋯O hydrogen bonds link the mol-ecules into helical chains parallel to the b axis. Intra-molecular O-H⋯O hydrogen bonds are also observed.

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عنوان ژورنال:

دوره 69  شماره 

صفحات  -

تاریخ انتشار 2013